Description
Quinine sulfate dihydratequick Details
Chemical Name: Quinine sulfate dihydrate
CAS No.: 6119-70-6
Molecular Formula: C40H48N4O4·H2SO4·2H2O
Chemical Structure:
Molecular weight:782.96
Appearance: White or almost white, crystalline powder or fine, colourless needles
Assay: 99.0-101.0
Quinine sulfate dihydratetypical Properties
Item
Specifications
Appearance
White or almost white, crystalline powder or fine, colourless needles
Solubility
Slightly soluble in water sparingly souluble in boiling water and in ethanol
PH
5.7-6.6
Specific optical rotation
-237- -245
Other cinchona alkaloids
ImpurityC ≤10%Any impurity eluted before quinine≤5.0%Anyotherimpurity≤2.5%
Loss on drying
3.0%-5.0%
Suiphated ash
≤0.1%
Assay
99.0-101.0
Quinine sulfate dihydrateUsage
Quinine sulfate is a quinoline derivative that binds to the DNA of Plasmodium and forms a complex that inhibits DNA replication and RNA transcription, thereby inhibiting protozoal protein synthesis, which is weaker than chloroquine. It is suitable for falciparum malaria caused by chloroquine and multi-drug resistant strains. It can also be used to treat vivax malaria. For asthma, atrial fibrillation and other serious heart conditions, patients with glucose-6-phosphate dehydrogenase deficiency and women’s menstrual period should be used with caution. Pregnant women are banned.
Quinine sulfate dihydratePackaging and Shipping
Packing: 25kg/drum
Delivery: have the stock
5-Acetyl-2,4-dimethylthiazoleStorage
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
