Trimethoprim CAS 738-70-5
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Chemical Name: Trimethoprim
CAS No.:738-70-5
Molecular Fomula:C10H11N3O3S
Molecular weight:253.28
Appearance:neat
Sample: Available

Trimethoprim: The Complete Guide
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Description of Trimethoprim
- Ipral(TMP) is an antibiotic used mainly in the treatment of bladder infections. Other uses include for middle ear infections and travelers’ diarrhea. With sulfamethoxazole or dapsone it may be used for Pneumocystis pneumonia in people with HIV/AIDS. It is taken by mouth.
- Common side effects include nausea, changes in taste, and rash. Rarely it may result in blood problems such as not enough platelets or white blood cells. May cause sun sensitivity. There is evidence of potential harm during pregnancy in some animals but not humans. It works by blocking folate metabolism via dihydrofolate reductase in some bacteria which results in their death.
- Trimethoprim was first used in 1962. It is on the World Health Organization’s List of Essential Medicines, the most important medications needed in a basic health system. It is available as a generic medication and is not very expensive. In the United States 10 days of treatment is about 21 USD.
Basic Info of Trimethoprim
Chemical Name | trimethoprim |
Synonyms | Monotrim;Proloprim;Monotrimin; Triprim;Trimpex;Expand |
CAS No. | 738-70-5 |
Molecular Formula | C14H18N4O3 |
Molecular Weight | 290.31800 |
PSA | 105.51000 |
LogP | 2.42000 |
Safety Info
RTECS | UV8225000 |
Hazard Class | 6.1(b) |
Safety Statements | S45 |
HS Code | 2933599090 |
Packing Group | III |
WGK Germany | 3 |
RIDADR | UN 3249 |
Risk Statements | R25 |
Hazard Codes | T |
Properties
Appearance & Physical State | white to yellowish powder |
Density | 1.252 g/cm3 |
Boiling Point | 526ºC at 760 mmHg |
Melting Point | 199-203ºC |
Flash Point | 271.9ºC |
Stability | Stable. Incompatible with strong oxidizing agents, acids. |
Storage Condition | 2-8ºC |
Numbering system
UNII | AN164J8Y0X |
What is Trimethoprim?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives.
- One such product is Ipral which has developed particularly rapidly in recent years. Do you know about Ipral?
- The official answer:Ipral, abbreviated as TMP, is an organic compound with the chemical formula C14H18N4O3, a white or to light yellow crystalline powder, odourless, bitter in taste, slightly soluble in chloroform, slightly soluble in ethanol or acetone, practically insoluble in water and soluble in glacial acetic acid.Methicillin is a synthetic broad-spectrum antibacterial agent, used alone for respiratory tract infections, urinary tract infections, intestinal infections, etc. It can be used to treat septicaemia, meningitis, otitis media, typhoid fever and shigellosis (bacillary dysentery) caused by sensitive bacteria.
What’s the application of Trimethoprim?
A new oral broad-spectrum antibacterial drug. The antibacterial spectrum is similar to that of sulphonamides but is more potent and effective against a wide range of gram-positive and negative bacteria. It is not suitable for use as an antibacterial agent on its own as bacteria will easily develop resistance to it. The combination of methotrexate and sulphonamides can enhance the antibacterial effect Chemicalbook several times to tens of times. It is mainly used as a synergist for sulphonamides. It is generally used in a ratio of 1:5. It can also be used as a veterinary medicine for the treatment of septicaemia caused by coliform hepatic bacteria in poultry, chicken dysentery, avian typhoid, cholera and secondary bacterial infections of the respiratory system. It can also be used for the treatment of coccidiosis.
Conclusion
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