1.1 NamePyridine hydrochloride1.2 Synonyms

EINECS 211-027-4MFCD00012802Pyridine chlorhydratePYRIDINE HCLPyridine hydrochloride (1:1)PYRIDINE HYDROCHLORIDE PYRIDINE HYDROCHLORIDEPyridine, hydrochloridePyridine, hydrochloride (1:1)pyridine,hydrochloridePYRIDINIUM CHLORIDEPYRIDINIUM MONOCHLORIDE

1.3 CAS No.

628-13-7

1.4 CID

10176127

1.5 EINECS(EC#)

211-027-4

1.6 Molecular Formula

C5H6ClN (isomer)

1.7 Inchi

InChI=1S/C5H5N.ClH/c1-2-4-6-5-3-1;/h1-5H;1H

1.8 InChIkey

AOJFQRQNPXYVLM-UHFFFAOYSA-N

1.9 Canonical Smiles

C1=CC=NC=C1.Cl

1.10 Isomers Smiles

C1=CC=NC=C1.Cl

2.1 Density

1.34

2.1 Melting point

140-146℃

2.1 Boiling point

222-224℃

2.1 Refractive index

1.5304 (estimate)

2.1 Flash Point

20 °C

2.1 Precise Quality

115.018875

2.1 PSA

12.89000

2.1 logP

1.88360

2.1 Solubility

ethanol: soluble50mg/mL, clear, colorless to light yellow

2.2 Appearance

White to tan Crystals

2.3 Storage

Hygroscopic. Ambient temperatures.

2.4 Chemical Properties

white to tan crystals

2.5 Color/Form

White to tan

2.6 Water Solubility

H2O: 85 g/100 mL;ethanol: soluble 50mg/mL, clear, colorless to light yellow

2.7 Spectral Properties

Index of refraction: 1.50920 @ 20 deg C/D
MAX ABSORPTION (CYCLOHEXANE): 251 NM (LOG E= 3.1); 256 NM (LOG E= 3.1); 279 NM (LOG E= 2.0) SHOULDER; 284 NM (LOG E= 1.8) SHOULDER; 288 NM (LOG E= 1.4) SHOULDER
IR: 4840 (Coblentz Society Spectral Collection)
UV: 9 (Sadtler Research Laboratories Spectral Collection)
NMR: 96 (Varian Associates NMR Spectra Catalogue)
MASS: 62073 (NIST/EPA/MSDC Mass Spectral Database, 1990 version)
Intense mass spectral peaks: 52 m/z, 79 m/z

2.8 Stability

Stable under normal temperatures and pressures.

2.9 StorageTemp

Inert atmosphere,Room Temperature

4.1 Symbol

GHS07

4.1 Hazard Codes

Xn

4.1 Signal Word

Warning

4.1 Risk Statements

R22;R36/37/38

4.1 Safety Statements

S26;S37/39

4.1 Exposure Standards and Regulations

Pyridine is a food additive permitted for direct addition to food for human consumption as a synthetic flavoring substance and adjuvant in accordance with the following conditions: a) they are used in the minimum quantity required to produce their intended effect, and otherwise in accordance with all the principles of good manufacturing practice, and 2) they consist of one or more of the following, used alone or in combination with flavoring substances and adjuvants generally recognized as safe in food, prior-sanctioned for such use, or regulated by an appropriate section in this part.

4.2 Octanol/Water Partition Coefficient

log Kow = 0.65

4.3 Other Preventative Measures

… HANDLING OF PYRIDINE SHOULD BE CONDUCTED IN WELL-VENTILATED CONDITIONS … .
Open lights and other /ignition sources/ capable of igniting pyridine and its vapor should be excluded from areas where pyridine is exposed in the course of manipulation.
Employees should wash immediately when skin is wet or contaminated. Remove clothing immediately if wet or contaminated to avoid flammability hazard. Provide emergency showers and eyewash.
Employees who handle liquid pyridine or solutions containing pyridine should wash their hands thoroughly before eating, smoking, or using toilet facilities.
If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without hazard. Use water spray to disperse vapors and dilute standing pools of liquid.
Personnel protection: Avoid breathing vapors. Keep upwind. Avoid bodily contact with the material. Do not handle broken packages unless wearing appropriate personal protective equipment.
If the use of respirators is necessary, the only respirators permitted are those that have been approved by the Mine Safety and Health Administration (formerly Mining Enforcement and Safety Administration) or by the National Institute for Occupational Safety and Health. In addition to respirator selection, a complete respiratory protection program should be instituted which includes regular training, maintenance, inspection, cleaning, and evaluation.
Clothing contaminated with liquid pyridine should be placed in closed containers for storage until it can be discarded or until provision is made for the removal of pyridine from the clothing. If the clothing is to be laundered or otherwise cleaned to remove the pyridine, the person performing the operation should be informed of pyridine’s hazardous properties. Non-impervious clothing which becomes contaminated with liquid pyridine should be removed immediately and not reworn until the pyridine is removed from the clothing.
… PROCESS PLANT SHOULD, BY PREFERENCE, BE ENCLOSED AND FITTED WITH LOCAL EXHAUST VENTILATION. DEPENDING ON THE EXTENT OF POSSIBLE CONTACT, WORKERS SHOULD BE PROVIDED WITH PERSONAL PROTECTIVE EQUIPMENT.
Skin that becomes wet with liquid pyridine should be promptly washed or showered. Eating and smoking should not be permitted in areas where liquid pyridine is handled, processed, or stored.
SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.
The worker should immediately wash the skin when it becomes contaminated.
Work clothing that becomes wet should be immediately removed due to its flammability hazard.
Eyewash fountains should be provided in areas where there is any possbility that workers could be exposed to the substance; this is irrespective of the recommendation involving the wearing of eye protection.

• COA (Certificate Of Analysis)