N-Bromosuccinimide CAS 128-08-5

Identification reagents

Used as an identification reagent for primary, secondary and tertiary alcohols.

Raw material for organic synthesis

Widely used in anionic and radical bromination reactions of olefins, alkynes and other compounds. It is used for the regulation of low-energy bromination reactions, for the production of rubber auxiliaries and for the commercial production of pharmaceuticals such as cortisone and vitamin D3, and for the synthesis of thiamethoxam in the pesticide industry.

Preservatives

Used as a preservative for fruit and as a preservative and anti-mould agent.

Important brominating agents

Used in allylic bromination (Wohl-Ziegler reaction) as a selective brominating agent for chain olefins and alkyl aromatics. In the pharmaceutical industry, it is used as a brominating agent in the synthesis of antimicrobial agents such as benzyl cephalosporins (Cefaloram).

Important oxidising agents

Oxidation of ethanol to aldehydes and ketones and oxidation of aldehydes to brominated acids in organic synthesis. Oxidation of silyl ethers to aldehydes in the presence of AIBN. Used in the oxidation of tryptophan, but tyrosine, histidine and methionine residues may be oxidised to a lesser extent.

Tryptophan reformer

Also used for the modification of ribosomal sulfhydryl groups.

General purpose brominating reagents

Used for the oxidation of tryptophan, although tyrosine, histidine and methionine oxidation residues may be present to a lesser extent; used for group modification of ribosomal sulfhydryl groups.

Ascorbic acid determination

Used to determine ascorbic acid in pharmaceutical preparations, biological fluids and vegetables and fruits.