N-Acetylneuraminic acid CAS 131-48-6
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Chemical Name: N-Acetylneuraminic acid
CAS No.: 131-48-6
Molecular Fomula: C11H19NO9
Molecular weight: 309.27
Appearance: Synthetic, crystalline
Sample: Available

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Description of N-Acetylneuraminic acid
N-Acetylneuraminic acid (Neu5Ac or NANA) is the predominant sialic acid found in mammalian cells.
This negatively charged residue is found in complex glycans on mucins and glycoproteins found at the cell membrane. Neu5Ac residues are also found in glycolipids, such as gangliosides, a crucial component of neuronal membranes found in the brain.
Along with involvement in preventing infections (mucus associated with mucous membranes— mouth, nose, GI, respiratory tract), Neu5Ac acts as a receptor for influenza viruses, allowing attachment to mucous cells via hemagglutinin (an early step in acquiring influenzavirus infection).
Basic Info of N-Acetylneuraminic acid
Chemical Name | N-acetylneuraminic acid |
Synonyms | SIALIC ACID;LACTAMINIC ACID;NANA;N-acetyl-D-neuraminic acid;5-Acetamido-3,5-dideoxy-D-glycero-D-galactononulosonic acid,Lactaminic acid,NAN;NANA TYPE IV-S;sialic acid powder;NEU5AC;N-Acetylneuraminic acid;5-Acetamido-3,5-dideoxy-D-glycero-D-galactononulosonic acid;NAN;NANA TYPE VI;NANA H2O;Sialomucin;Aceneuramic acid. |
CAS No. | 131-48-6 |
Molecular Formula | C11H19NO9 |
Molecular Weight | 309.27000 |
PSA | 176.78000 |
LogP | -3.48090 |
Safety Info
Safety Statements | S24/25 |
HS Code | 2932999099 |
WGK Germany | 3 |
Risk Statements | R36/37/38 |
Hazard Codes | Xi |
Properties
Appearance & Physical State | Crystalline |
Density | 1.727 g/cm3 |
Boiling Point | 395.6ºC at 760 mmHg |
Melting Point | 184-186ºC |
Flash Point | 193ºC |
Refractive Index | -32 ° (C=1, H2O) |
Water Solubility | 50 g/L (20 ºC) |
Stability | Stable. Incompatible with strong oxidizing agents. |
Storage Condition | -20ºC |
Vapor Pressure | 5.5E-30mmHg at 25°C |
Numbering system
MDL number | MFCD00006620 |
BRN number | 1716283 |
PubChem number | 24890457 |
EINECS number | 205-023-1 |
What is N-Acetylneuraminic acid?
With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is N-Acetylneuraminic acid which has developed particularly rapidly in recent years. Do you know about N-Acetylneuraminic acid?
The official answer: N-Acetylneuraminic acid is the most widely distributed sialic acid in nature and is mainly a constituent sugar of glycoproteins, glycolipids or bacterial podoconjugates of animal cell membranes or secretory fluids.
What’s the application of N-Acetylneuraminic acid?
Substrate for the action of N-acetylneuraminic acid aldolase.
Conclusion
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