Description
Moxidectin Details
Chemical Name:Moxidectin
CAS No.:113507-06-5
Molecular Formula: 113507-06-5
Molecular Weight: 639.825
MolecularStructure:
Appearance: White or pale yellow amorphous powder
Moxidectin Typical Properties
Item
Specifications
Results
Appearance
White or pale yellow amorphous powder
White amorphous powder
Identification
IR spectrum of sample corresponds to that of reference substance
Comply
The retention time of the major peak of the sample solution corresponds to that of the standard solution, as obtained in the assay
Comply
Water
≤1.3 %
0.6 %
Residue on ignition
≤0.2 %
0.04 %
Heavy Metals
≤20 ppm
＜ 20 ppm
Assay( anhydrous basis )
92.0 % – 102.0 %
98.2 %
Organic impurities
Early-eluting impurities
Moxidectin butenyl analog ( A ) ≤1.5 %
0.1 %
5’-Demethyl moxidectin( B ) ≤0.5%
0.2 %
Moxidectin pentenly analog ( C ) ≤1.5 %
0.4 %
Moxidectin 17a-epimer ( D ) ≤2.5%
0.2 %
Sum of moxidectin 19-S-17a-ene and moxidectin ethyl isomers (E F ) ≤1.7 %
0.3 %
Milbemycin B analog ( moxidectin open ring ) ( G ) ≤1.5 %
Not detected
Any other individual impurity eluting before milbemycin B analog ( moxidectin open ring ) ≤0.5 %
0.2 %
Late-eluting impurities
Moxidectin deoxydienea and 4’-Methylthiomethoxymoxidectin ( H I ) ≤1.0 %
Not detected
20b-Methylthiomoxidectin( J ) ≤0.5 %
Not detected
20-Nitrobenzoylmoxidectin( K ) ≤0.5 %
Not detected
Any other individual impurity eluting after the milbemycin B analog (moxidectin open ring ) ≤0.5 %
Not detected
Total organic impurities
≤7.0 %
1.7 %
Solvent residue
Methanol ≤3000 ppm
Not detected
Methylene chloride ≤300 ppm
Not detected
Isopropyl acetate ≤5000 ppm
Not detected
N-heptane ≤3000 ppm
72 ppm
BHT
0.3 % – 0.6 %
0.49 %
Conclusion
The product complies with the specification ( USP )
Storage
Preserve in well-closed, light-resistant containers, and store in room temperature .
Moxidectin Usage
1. Moxidectin can be used as a veterinary anthelmintic.
2. As a new generation of deworming drugs, moxidectine can effectively kill nematodes and surface parasites.It is quite safeto animals.
3. It is superior to ivermectin in dosage, formulation development, drug resistance and drug distribution in vivo.
Moxidectin Packaging and Shipping
Packing: 25kg/drum
Moxidectin Storage
Stored in a cool dry and sealed container away from children
