Description
Milbemycin Oxime Details
Chemical Name:Milbemycin Oxime
CAS No.:129496-10-2
Molecular Formula:2C32H45NO7.2C31H43NO7
Molecular Weight:2194.78
MolecularStructure:
Appearance: White or light yellow amorphous powder
Milbemycin Oxime Typical Properties
Item
Specifications
Results
Appearance
White orlight yellow amorphous powder
White amorphous powder
Identification
IR spectrum of sample corresponds to that of reference substance
Comply
The retention time of the major peak of the sample solution corresponds to that of the standard solution, as obtained in the assay
Comply
Water
≤3.0 %
1.0 %
Residue on ignition
≤0.5 %
0.1 %
Assay
( Sum of Milbemycin A4 oxime and Milbemycin A3 oxime) : 95.0%-102.0 on the anhydrous basis .
98.1 %
Ratio of Milbemycin A4 oxime ≥ 0.75
0.94
Ratio of Milbemycin A3 oxime ≥ 0.25
0.06
Organic impuritis
Impurity a: 11’DesmethylMilbemycin A4 oxime ≤0.7 %
0.06 %
Impurity b: (20’R)-Hydroxymilbemycin A4keto form ≤0.5%
0.1 %
Impurity c: Milbemycin A4 keto form ≤0.7 %
0.4 %
Impurity d: Milbemycin D oxime ≤3.0%
0.2 %
Any other individual impurity ≤0.5 %
0.2 %
Total impurities ( excluding impurity d ) ≤3.5 %
1.3 %
Reporting threshold: 0.10 %
0.2 %
Solvent residue
Trichloromethane ≤60 ppm
Not detected
N-Heptane ≤5000 ppm
2 ppm
Ethanol ≤5000 ppm
24 ppm
Conclusion
The product complies with the specification ( USP )
Storage
Preserve in tight containers, and store at room temperature , protected from light .
Milbemycin Oxime Usage
1.It is a special medicine for preventing and treating parasites in dogs and cats.
2.It can effectively control heartworms and prevent endoparasites such as hookworms, roundworms, whipworms and aphids, as well as hair follicles, mites, ticks, fleas, etc.
Milbemycin Oxime Packaging and Shipping
Packing: 25kg/ drum
Milbemycin Oxime Storage
Stored in a cool dry and sealed container away from children
