Miconazole nitrate Typical Properties
Appearance
White or off white powder
Identification
IR
Similar to Standard
UV
Similar to Standard
Appearance of Solution
The solution is clear and not more intensely cloured than reference solution Y7
Related Substance
Each impurity
≤0.25%
Total impurity
≤0.5%
Purity(TLC) – Individual Iimpurity
≤0.25%
Optical Rotation
-0.1～+0.1
Melting Point
178 – 184 ℃
Loss on Drying
≤0.5%
Residual on Ignition
≤0.1%
Assay(On Dry Basis)
98.0 – 102.0%
Brand name
Fousi chemical
Miconazole nitrate Usage
Miconazole nitrate is an antifungal drug, which is the familiar drug commonly used to treat skin ringworm, Dakron. It inhibits the biosynthesis of ergosterol, a component of fungal cell membranes, destroys the structure of the cell membrane and increases the permeability of the cell membrane , Leading to the leakage of intracellular components and inhibiting the use of glucose, preventing nutrient uptake, and ultimately causing fungal cell death.
It is suitable for the treatment of tinea corporis, tinea corporis, tinea pedis, tinea pedis, tinea versicolor, fungal paronychia, and vaginal infections and secondary caused by yeasts (such as Candida, etc.) and Gram-positive bacteria. Infection is also effective for otitis externa and bacterial skin infections.
Common adverse reactions and side effects of miconazole nitrate include: occasional allergies, blisters, burning sensation, hyperemia, itching, or other skin irritation symptoms. Angioedema, urticaria, eczema, contact dermatitis, erythema, pelvic pain (spasm), vaginal irritation, vaginal discharge, and discomfort at the administration site are very rare.
Miconazole nitrate Packaging and Shipping
Packing: 25kg/drum
Miconazole nitrate Storage
Stored in cool dry ventilated place away from fire, heat, light, acids and food materials
