Glutathione CAS# 70-18-8
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Chemical Name: Glutathione
CAS No.: 70-18-8
Molecular Fomula: C11H14O
Molecular FormulaC10H17N3O6S
Average mass32
Appearance:White Powder
Sample: Available
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Description of Glutathione
Glutathione may decrease the concentrations of inflammatory cytokines (IL-6, IL-18), neutrophils in lung tissue and increase the level of serum Ca2+ and be useful for the treatment of ANP. Glutathione production is regulated via distinct pathways in stressed and non-stressed cortical neurons.
Basic Info of Glutathione
Chemical Name | Glutathione |
|---|---|
Synonyms | Reduced glutathione;Isethion;L-Glutathione;Deltathione;L-Glutathione Reduced;Expand |
CAS No. | 70-18-8 |
Molecular Formula | C10H17N3O6S |
Molecular Weight | 307.32300 |
PSA | 197.62000 |
LogP | -0.72400 |
Safety Info
Safety Statements | S24/25 |
|---|---|
HS Code | 2930909090 |
Risk Statements | R68 |
Hazard Codes | Xi |
Properties
Appearance & Physical State | White Powder |
|---|---|
Density | 1.441 g/cm3 |
Boiling Point | 410.1ºC |
Melting Point | 182-192ºC |
Refractive Index | 1.571 |
Stability | Stable. Incompatible with strong oxidizing agents. |
Storage Condition | 2-8ºC |
Numbering system
| MDL number | MFCD00065939 |
|---|
What is Glutathione?
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The official answer:
Glutathione (r-glutamyl cysteingl +glycine, GSH) is a tripeptide containing a gamma-amide bond and a sulfhydryl group, consisting of glutamate, cysteine and glycine, and is present in almost every cell of the body .
Glutathione helps to maintain normal immune system function and has antioxidant effects and integrates detoxification . The sulfhydryl group on cysteine is its active group (so it is often abbreviated as G-SH), which binds to certain drugs and toxins, making it an integrative detoxifier . Glutathione can be used not only as a drug but also as a base for functional foods, which are used in functional foods such as delaying aging, enhancing immunity, and anti-tumor. .
Glutathione is available in both reduced (G-SH) and oxidized (G-S-S-G) forms, with reduced glutathione predominating under physiological conditions. Glutathione reductase catalyzes the interchange between the two forms, and the coenzyme of this enzyme also provides the NADPH for pentose phosphate bypass metabolism
What’s the application of Glutathione?
UsesReduced glutathione is a small molecule peptide, which exists in large quantities in living organisms, especially in liver cells, and has the function of protecting liver cell membranes and promoting liver enzyme activity, and plays the role of detoxification by combining with many toxic chemicals. It has good effect on drug poisoning, alcohol poisoning and other diseases caused by various reasons such as liver injury and cirrhosis of the liver. Uses: Antioxidant, free radical scavenging, detoxification, immunity enhancement, aging delay, anti-cancer, anti-radiation hazard, etc.
Uses: Biochemical reagent, detoxification Chemicalbook medicine, mainly used for heavy metal, acrylonitrile, fluoride, carbon monoxide and organic solvents and other poisoning
Use biochemical research use endogenous antioxidant that plays an important role in the reduction of reactive oxygen species formed during cell metabolism and sudden respiration. Glutathione-S-transferase catalyzes the formation of glutathione sulfide with xenobiotics, leukotrienes and other molecules with electrophilic centers. Glutathione also forms disulfide bonds with cysteine residues in proteins. Through these mechanisms, it may have the singular effect of reducing the potency of anticancer agents.
Conclusion
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