Epothilone D CAS 189453-10-9

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Chemical Name: Epothilone D

CAS No.:189453-10-9

Molecular Fomula:C27H41NO5S

Molecular weight:491.68

Sample: Available

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Epothilone D CAS#189453-10-9

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Description of Epothilone D

Epothilones are polyketide natural products that inhibit cancer cells by a mechanism similar to paclitaxel, and also are effective against paclitaxel-resistant tumours. Epothilone D is in phase I clinical testing of in patients with advanced solid tumours. Epothilone D is a cytotoxic macrolide that stabilises malignant cells’ microtubules and arrests mitosis, a characteristic it shares with other epothilones. They bind to the same hepatic sites as does paclitaxel (Taxol) in a 1:1 stoichiometric ratio of a, b-tubulin heterodimers.

Basic Info of CS-1161

Chemical Name

epothilone D

Synonyms

Epothilone D;Epo A;desoxyepothilone B;epithilone A;Epothilones;Expand

CAS No.

189453-10-9

Molecular Formula

C26H39NO5S

Molecular Weight

477.65700

PSA

124.96000

LogP

4.87620

Numbering system

UNII

T0358E0YUF

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What is Epothilone D?

With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is CS-1161 which has developed particularly rapidly in recent years. Do you know about CS-1161?

The official answer:Epothilone is a class of macrolides first reported in 1993 by G. Höfle et al. of the German National Centre for Biotechnology (GBF). Epothilone can be isolated from the fermentation broth of a strain of the mucilaginous suborder Clostridium fibrillarum, the main components of which are Epothilone A and B.

What’s the application of Epothilone D?

It is used in the treatment of colon, breast and ovarian cancers.

The overview, preparation and application of Epothilone B was compiled by Ding Hong of Chemicalbook

Conclusion

Sincere to the customer and in good faith of quality is our forever followed motto. It’s the basement to be a human and do business. We take all responsibility for our products and service sincerely. We are a company integrating R&D, production, and sales. The design, research, and development of pharmaceutical intermediates include more than 330 kinds of pharmaceutical intermediates such as Anti-infectives, Cardiovascular and Cerebrovascular Systems, Digestive systems, Santi-tumor, Nervous systems, Geriatric Drugs, and Gynecological Drugs. At the same time, we have more than 4,000 factories in strategic cooperation with nearly 50,000 chemical products, so we can provide you with a one-stop purchasing service, which greatly saves customers’ procurement costs and time.

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Hi, I‘m Peter Ni, the founder of Sincere-Chem, I’ve been running a company in China that exporting chemicals, pharmaceuticals, and intermediates for over 70 countries now. And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.

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Keywords of Epothilone D

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United Kingdom Giles
United Kingdom Giles
Peter has been my partner for many years, we met at the Shanghai CPHI Fair in 2014, for the first time I didn't have much interest in Peter's products because our company had a stable supplier. Although we didn't work together, Peter would often send me important news and interesting trend information about the industry, so we became good friends, even though I didn't place any orders with him during this time, even if it was a sample order. In September 2016, our original supplier was unable to provide us with the quality and delivery guarantees we needed, so I first thought of Peter and his company. Until now, we have maintained a very good personal friendship in addition to a steady business relationship.
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Mexico Gonzalo
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