diisopropylethylamine CAS 7087-68-5
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Chemical Name: diisopropylethylamine
CAS No.:7087-68-5
Molecular Fomula:C8H19N
Molecular weight:129.24
Appearance:APHA: <20 Liquid
Sample: Available

diisopropylethylamine: The Complete Guide
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Description of diisopropylethylamine
- N,N-DIEA, or Hünig’s base, DIPEA or DIEA, is an organic compound and an amine. It is used in organic chemistry as a base. Because the nitrogen atom is shielded by the two isopropyl groups and an ethyl group only a proton is small enough to easily fit. Like 2,2,6,6-tetramethylpiperidine, this compound is a good base but a poor nucleophile, which makes it a useful organic reagent. Hünig’s base is named after the German chemist Siegfried Hünig. The compound is a colourless liquid.
- Hünig’s base is commercially available. It is traditionally prepared by the alkylation of diisopropylamine with diethyl sulfate. If necessary, the compound can be purified by distillation from potassium hydroxide.
Basic Info of diisopropylethylamine
Chemical Name | Ethyldiisopropylamine |
Synonyms | N-ethyl-N-propan-2-ylpropan-2-amine;2-Propanamine, N-ethyl-N-(1-methylethyl)-; |
CAS No. | 7087-68-5 |
Molecular Formula | C8H19N |
Molecular Weight | 129.24300 |
PSA | 3.24000 |
LogP | 2.12510 |
Safety Info
Hazard Class | 3 |
Safety Statements | S16-S26-S36/37/39-S45-S61 |
HS Code | 2942000000 |
Packing Group | II |
WGK Germany | 2 |
RIDADR | UN 1993/2733 |
Risk Statements | R11; R22; R34; R52/53 |
Hazard Codes | F; C |
Symbol | GHS02, GHS05, GHS06, GHS08 |
Signal Word | Danger |
Caution Statement | P201; P261; P280; P304 + P340 + P312; P305 + P351 + P338 + P310; P308 + P313 |
Hazard Declaration | H226; H302; H315; H318; H331; H335; H360D |
Properties
Appearance & Physical State | clear, colorless to light yellow liquid |
Density | 0.782 |
Boiling Point | 127ºC |
Melting Point | -46ºC |
Flash Point | 6ºC |
Refractive Index | 1.4123-1.4143 |
Water Solubility | miscible |
Storage Condition | Store in dark |
Numbering system
MDL number | MFCD00008868 |
What is diisopropylethylamine?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives.
- One such product is DIEA which has developed particularly rapidly in recent years. Do you know about DIEA?
- The official answer:Colourless transparent liquid, soluble in alcohols, ethers and other organic solvents, alkaline, flammable, volatile, with the odour of amines and irritating. Irritating to eyes, skin, mucous membranes and upper respiratory tract. Inhalation causes inflammation of the larynx and bronchi, oedema, spasm, chemical pneumonia and pulmonary oedema. Exposure can cause burning sensation, coughing, wheezing, shortness of breath, headache, nausea and vomiting.
What’s the application of diisopropylethylamine?
N,N-DIEA is a colourless and transparent liquid, insoluble in water and soluble in acetone and other organic solvents.DIPEA is an important pesticide and pharmaceutical intermediate, which can be used to synthesize anaesthetics and herbicides, and can also participate in various catalytic reactions as a site-blocking amine.
Conclusion
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