Description
Brefeldin A Quick Details
Chemical Name: Brefeldin A
CAS No: 20350-15-6
Molecular Formula: C16H24O4
Molecular Weight: 280.36
Chemical Structure:
Appearance: A white crystalline powder
Assay: 98%
Brefeldin A Typical Properties
Item
Specifications
Appearance
A white crystalline powder
Solubility
Soluble in methanol, chloroform
Water
≤3%
Heavy Metals
<20ppm
Total Impurities(HPLC)
≤2%
Purity(HPLC)
≥98%
Brefeldin A Usage
1. Brefeldin A, a commonly used protein transport inhibitor, specifically reversibly blocks the transport of proteins from the endoplasmic reticulum (ER) to the Golgi.
2. After Brefeldin A treatment, the Golgi apparatus is quickly destroyed and fused to the endoplasmic reticulum, which exhibits energy, temperature and microtubule dependence.
3. In mammals and yeast, Brefeldin A inhibition of protein transport from the endoplasmic reticulum to the Golgi apparatus may be achieved by a class of GTP-exchange factors that activate Afr1p GTPase.
4. Arf1p forms transport vesicles by recruiting coat proteins to the inner membrane of the cell.
Brefeldin APackaging and Shipping
Packing: Bottle
Delivery: Express or air
Brefeldin AStorage
A cool, ventilated, dry place.
