Albendazole CAS# 54965-21-8
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Chemical Name: Albendazole
CAS No.: 54965-21-8
Molecular FormulaC12H15N3O2S
Average mass331
Appearance: Colourless Crystalline Solid
Sample: Available

Albendazole : The Complete Guide
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Description of Albendazole
Albendazole, marketed as Albenza among others, is medication used for the treatment of a variety of parasitic worm infestations. It is useful for giardiasis, trichuriasis, filariasis, neurocysticercosis, hydatid disease, pinworm disease, and ascariasis, among others. It is taken by mouth.
Common side effects include nausea, abdominal pains, and headaches. Potentially serious side effects include bone marrow suppression which usually improves on stopping the medication. Liver inflammation has been reported and those with prior liver problems are at greater risk. It is pregnancy category C in the United States and category D in Australia, meaning it may cause harm if taken by a pregnant women. Albendazole is a broad-spectrum antihelminthic agent of the benzimidazole type.
Albendazole developed in 1975. It is on the World Health Organization’s List of Essential Medicines, the most important medications needed in a basic health system. The wholesale cost in the developing world is between 0.01 and 0.06 USD per dose. In the United States, however, it is very expensive as of 2014 at about 50 USD per dose.
Basic Info of Albendazole
Chemical Name | albendazole |
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Synonyms | ALBENZA;methyl-5-propylthio-2-benzimidazole carbamate;Bruzol;methyl N-[5-(propylthio)-1H-benzimidazol-2-yl]carbamate;Albendazole;Expand |
CAS No. | 54965-21-8 |
Molecular Formula | C12H15N3O2S |
Molecular Weight | 265.33100 |
PSA | 92.31000 |
LogP | 3.31630 |
Safety Info
RTECS | FD1100000 |
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Safety Statements | S53; S45; S37/39; S26 |
HS Code | 3004909090 |
WGK Germany | 2 |
Risk Statements | R61; R36/37/38 |
Hazard Codes | T |
Properties
Appearance & Physical State | Colourless Crystalline Solid |
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Melting Point | 208-210 °C |
Storage Condition | 0-6°C |
Numbering system
MDL number | MFCD00083232 |
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What is Albendazole?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Ambroxan which has developed particularly rapidly in recent years. Do you know about Ambroxan?
- The official answer: Albendazole is an imidazole derivative broad-spectrum anthelmintic drug. It was discovered by GlaxoSmithKline’s Animal Health Laboratory in 1972. Albendazole is included in the World Health Organization’s Essential Medicines Standard List and is one of the most important essential health medicines.
Albendazole is a highly effective and low-toxic broad-spectrum anthelmintic. It can be used clinically against roundworms, pinworms, tapeworms, whipworms, hookworms, and fecal nematodes. After metabolized to sulfoxide or sulfone in the body, it inhibits the uptake of glucose by the parasite, leading to glycogen depletion of the worm, or inhibits the yohimbe acid reductase system, hindering the production of ATP and preventing the parasite from surviving and reproducing.
What’s the application of Albendazole?
- It is used as an anthelmintic, effective against both gastrointestinal nematodes and liver flukes in animals. It can with feed. It is a effective broad-spectrum anthelmintic, and is one of the benzimidazoles with the broadest anthelmintic spectrum and strongest anthelmintic effect. It can to remove roundworms, pinworms, hookworms, whipworms, treat various types of cysticercosis, and also for deworming of domestic animals.
- It to prevent and control cabbage downy mildew, rice blast, tobacco powdery mildew, anthrax, etc. Broad-spectrum anthelmintic. It can to expel roundworms, pinworms, tapeworms, whipworms, etc.
- It is an efficient and broad-spectrum anthelmintic drug, which has significant effects on liver fluke, tapeworm, lung and gastrointestinal nematodes. It is one of the strongest benzimidazoles and is the first choice for the prevention and treatment of parasitic diseases in livestock and poultry. The product is effective against adult liver fluke and larvae of cattle and sheep, and large slices of trematodes, and the reduction rate can reach 90-100%. In recent years, it has \to have a strong effect on bovine cysticercus, and after treatment, the cysticercus is reduced and the lesions disappear. Besides, it can also \ to prevent parasitic infections, so it can be more effective in promoting the growth of sheep and increasing wool production.
- It is a effective broad-spectrum anthelmintic. It can block the absorption of various nutrients and glucose by the worm, resulting in the depletion of the worm’s glycogen, making it impossible for the parasite to survive and reproduce. It\ to treat single or mixed sense caused by roundworms, pinworms, whipworms, hookworms, etc. It binds microtubule proteins and inhibits the polymerization of microtubules.
- UsesA broad-spectrum anti-parasitic agent of the benzimidazole class.
Conclusion
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