2,6-Pyridinedicarboxylic acid
CAS# 499-83-2

2,6-Pyridinedicarboxylic acid CAS# 499-83-2 , Promotion Season Now in Store and Free Sample for Testing with Factory Price

Chemical Name: 2,6-Pyridinedicarboxylic acid
CAS No.: 499-83-2
Molecular Formula: C7H5NO4
Molecular weight: 167.12
Sample: Available

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2,6-Pyridinedicarboxylic acid CAS# 499-83-2

2,6-Pyridinedicarboxylic acid CAS# 499-83-2: The Complete Guide

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Description of 2,6-Pyridinedicarboxylic acid CAS# 499-83-2

  • Dipicolinic acid (pyridine-2,6-dicarboxylic acid or PDC and DPA) is a chemical compound which composes 5% to 15% of the dry weight of bacterial spores. It is implicated as responsible for the heat resistance of the endospore.
  • However, mutants resistant to heat but lacking dipicolinic acid have been isolated, suggesting other mechanisms contributing to heat resistance are at work.
  • Dipicolinic acid forms a complex with calcium ions within the endospore core. This complex binds free water molecules, causing dehydration of the spore. As a result, the heat resistance of macromolecules within the core increases. The calcium-dipicolinic acid complex also functions to protect DNA from heat denaturation by inserting itself between the nucleobases, thereby increasing the stability of DNA.
  • Two genera of bacterial pathogens are known to produce endospores: the aerobic Bacillus and anaerobic Clostridium.
  • The high concentration of DPA in and specificity to bacterial endospores has long made it a prime target in analytical methods for the detection and measurement of bacterial endospores. A particularly important development in this area was the demonstration by Rosen et al. of an assay for DPA based on photoluminescence in the presence of terbium, though ironically this phenomenon was first investigated for using DPA in an assay for terbium by Barela and Sherry. Extensive subsequent work by numerous scientists has elaborated on and further developed this approach.
  • It is also used to prepare dipicolinato ligated lanthanide and transition metal complexes for ion chromatography.

Basic Info of 2,6-Pyridinedicarboxylic acid CAS# 499-83-2

Chemical Name

dipicolinic acid

Synonyms

DPA,DPAc,Dipicolinic acid;RARECHEM AL BO 1335;IFLAB-BB F0451-0137;pyridine-2,6-dicarboxylic acid;dipicolinic;pyridine-2,6-carboxylic acid;2,6-DIPICOLINIC ACID;Dipicolinic Acid;2,6-pyridine dicarboxylic acid;2,6-Dicarboxypyridine;2,6-pyridinecarboxylic acid;‘DIPICOLINIC ACID’;2,6-Pyridinedicarboxylic acid;pyridine-2,6-dicarboxylic;2,5-DIMETHYL-3-ETHYLBENZOTHIAZOLIUM ETHYLSULFATE

CAS No.

499-83-2

Molecular Formula

C7H5NO4

Molecular Weight

167.11900

PSA

87.49000

LogP

0.47800
Safety Info

HS Code

29333999

WGK Germany

3
Properties

Appearance & Physical State

White crystalline powder

Density

1.551g/cm3

Boiling Point

463.7ºC at 760mmHg

Melting Point

248-250 °C (dec.)(lit.)

Flash Point

188 °C

Water solubility

5 g/L (20 ºC)

Numbering system
MDLMFCD00006299
EINECS207-894-3
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What is 2,6-Pyridinedicarboxylic acid CAS# 499-83-2?

With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is 2,6-Pyridinedicarboxylic acid which has developed particularly rapidly in recent years. Do you know about 2,6-Pyridinedicarboxylic acid?

The official answer: Pyridine-2,6-dicarboxylic acid, an organic chemical, formula: C7H5NO4.

What’s the application of 2,6-Pyridinedicarboxylic acid CAS# 499-83-2?

  • Pharmaceutical Intermediate，Pyridine-2,6-dicarboxylic acid is released from the spores of Thermophilus stearum by autoclaving; it induces the aggregation of chitosan-stabilized gold nanoparticles and changes the color of the solution from red to blue.It is used as a Competitive inhibition for Glutamate dehydrogenase of bovine liver and for preparing lanthanum dipicolinato and ligand complexes of transition metals

Conclusion

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