Trehalose CAS 99-20-7
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Chemical Name: Trehalose
CAS No.: 99-20-7
Molecular Fomula: C12H22O11
Molecular weight:342.3
Appearance:White to Off-white Powder
Sample: Available
Trehalose: The Complete Guide
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Description of Trehalose
Trehalose, also known as mycose or tremalose, is a natural alpha-linked disaccharide formed by an α,α-1,1-glucoside bond between two α-glucose units. In 1832, H.A.L. Wiggers discovered trehalose in an ergot of rye, and in 1859 Marcellin Berthelot isolated it from trehala manna, a substance made by weevils, and named it trehalose. It can be synthesised by bacteria, fungi, plants, and invertebrate animals. It is implicated in anhydrobiosis — the ability of plants and animals to withstand prolonged periods of desiccation. It has high water retention capabilities, and is used in food and cosmetics. The sugar is thought to form a gel phase as cells dehydrate, which prevents disruption of internal cell organelles, by effectively splinting them in position. Rehydration then allows normal cellular activity to be resumed without the major, lethal damage that would normally follow a dehydration/rehydration cycle. Trehalose is not an antioxidant, because it is a non-reducing sugar and does not contain nucleophilic groups in its molecule. However, it was reported to have antioxidant effects.
Extracting trehalose was once a difficult and costly process, but circa the year 2000, the Hayashibara company (Okayama, Japan) confirmed an inexpensive extraction technology from starch for mass production.
Trehalose is used in a broad spectrum of applications.
Basic Info of Trehalose
Chemical Name | α,α-trehalose |
Synonyms | α-D-Glucopyranoside, α-D-glucopyranosyl;TREHALOSE;D-(+)-Trehalose Anhydrous;alpha,alpha-trehalose; |
CAS No. | 99-20-7 |
Molecular Formula | C12H22O11 |
Molecular Weight | 342.29600 |
PSA | 189.53000 |
LogP | -5.39720 |
Safety Info
Safety Statements | S24/25 |
HS Code | 2940000000 |
Risk Statements | R38 |
Hazard Codes | Xi |
Properties
Appearance & Physical State | white to off-white crystalline powder |
Density | 1.76 g/cm3 |
Boiling Point | 675.4ºC at 760 mmHg |
Melting Point | 214-216ºC |
Flash Point | 362.3ºC |
Refractive Index | 197 ° (C=7, H2O) |
Numbering system
UNII | B8WCK70T7I |
What is Trehalose?
With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Trehalose which has developed particularly rapidly in recent years. Do you know about Trehalose?
The official answer:Alginate is formed by the condensation of two glucose molecules through a hemiacetal hydroxyl group and is a non-reducing disaccharide with the molecular formula C12H22O11 (containing two crystalline waters) as there is no free aldehyde group. As two glucose molecules can form α-glucopyranose and β-glucopyranose, three isomers can be obtained by linking them through α-1,1 glycosidic bonds: alginate (α,α), iso-alginate (β,β) and neo-alginate (α,β).
What’s the application of Trehalose?
It has the special function of preserving biological vitality and can effectively protect the structure of cell membranes and proteins, so that the organism remains moist inside the cell under abnormal conditions, such as high temperature dehydration (drying, high osmotic pressure) and freezing, preventing the loss of nutrients and cell damage due to water loss. Moreover, in vitro alginate also has the property of stabilizing biological membranes and protein structures, which is used internationally to protect genetically engineered enzymes, various viruses, vaccines, antibodies, protein factors, nucleic acids, etc. It is also used as a stabilizer and protector of biologically active substances, and has broad application prospects in food, health products, cosmetics, medicine, molecular biology and agriculture.
Conclusion
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