Doxorubicin hydrochloride Typical Properties
Items
Requirements
Results
Description
Orange-Red Crystalline powder，Hygroscopic，NoVisible Evidence Of Contamination By ForeignMaterial
Pass
Assay
98.0~102.0%
99.52%
Solubility
Solubility in water,Slightly Solubility in methanol；Practically insolubility in Chloroform and DiethylEther
Pass
Identification
The retention time of the Doxorubicin peak in thechromatogram of the test preparation corresponds tothat in the chromatogram of the standard preparation
Pass
PH
4.0~5.5
5.08
Moisture
<4.0%
1.33%
Chromatographic purity
Total impurities：<2.0%
<0.32%
Solvent Residues
Acetone<0.5%; Acetone &Alcohol<2.5%
0.11%；0.39%
Doxorubicin hydrochloride Usage
Doxorubicin is an anti-tumor antibiotic that inhibits the synthesis of RNA and DNA. It has the strongest inhibitory effect on RNA, has a broad anti-tumor spectrum, and has a role in various tumors. It is a non-specific drug of the cycle. Tumor cells of various growth cycles have a killing effect
Anti-tumor antibiotics, which have the effect of doxorubicin in cardiac mitochondrial DNA. Inhibitors of reverse transcriptase and RNA polymerase, immunosuppressive agents; can be inserted into DNA strands. Clinically, it is a cancer chemotherapy agent, mainly used for acute and chronic leukemia and malignant lymphoma.
Adriamycin hydrochloride is an antibiotic anticancer drug that can penetrate into cells and cross the DNA of tumor cells, bind, inhibit DNA replication, block the action of RNA polymerase, inhibit the synthesis of RNA; its cytotoxicity and freedom Base formation, associated with tumor cell membrane binding and fast cell membrane; widely used in cell culture or rat kidney disease, myocardial ischemia and other modeling materials; used to inhibit macromolecular biosynthesis
For the treatment of acute lymphoblastic leukemia, acute myeloid leukemia, Hodgkin’s disease and non-Hodgkin’s lymphoma, breast cancer, lung cancer, ovarian cancer
Doxorubicin hydrochloride Packaging and Shipping
Packing: Bag, Net weight: 1kg per Bag
Doxorubicin hydrochloride Storage
The warehouse is ventilated and dry at low temperature; it is stored separately from food materials.
